Mortality, Homocysteine and Related Nutrients: NDNS 65+
Bates CJ et al Br J Nutr. 2010;104:893-899
•n =1100, 50.2% Female.  Baseline 1994/5; follow-up Sept 2008
•Mortality data and cause were collected – related to baseline data
•Mortality predictable by; plasma tHcys, pyridoxal PO4, creatinine, Glyc Hb, alpha1-antichymotrypsin, fibrinogen, diet, but not folate/vit B12 intake/status
95% CI
Hazard Ratio
95% CI
Hazard Ratio
0.67, 0.94
0.79
0.77, 0.97
0.86
Protein g/day
0.79, 1.08
0.92
0.94, 1.29
1.1
Fat g/day
0.72, 1.02
0.86
0.8, 0.96
0.87
Energy KJ/day
1.05, 1.49
1.25
1.10, 1.31
1.20
Pl. Creatinine
1.11, 1.57
1.32
1.14, 1.32
1.23
Blood HbAIc%
0.73, 1.08
0.89
0.83, 0.99
0.90
Total Chol mmol/l
1.13, 1.63
1.36
1.11, 1.27
1.19
Pl. tHcys umol/l
Vascular Disease Mortality
died =199, alive =351
All-cause Mortality
died =749, alive =351
Biochemical Measure or
Dietary Factor