NDNS 65+: Determinants of Longevity
•During 14 yrs of follow-up the causes of death were recorded for free-living people; 74% of men and 62% of women died
•
•Mortality was predicted by baseline measures of:
- poor grip strength (men)
- low intakes of food and protein
- poor renal function - raised plasma creatinine and homocysteine
- raised Hb A1c  - prediabetes/diabetes
•Mortality also predicted by plasma levels of nutrients:
- raised copper - infection, cancer, liver or inflammatory disease
- raised plasma retinol – high intake, renal impairment, alcohol XS
- low vitamin C
- low alpha-carotene
- low vitamin B6
- low vitamin D (men)
- low zinc and selenium
•
•Mortality was not predicted by:
- dietary intakes of folate and vitamin B12
- haemoglobin, serum/plasma vitamin B12, folate and beta-carotene
- serum cholesterol