NDNS 65+ Abnormal Liver Function Tests
Prevalence of: Plasma Alkaline Phosphatase >110 IU/L
Plasma Gamma-Glutamyl Transferase >50/32 IU/L
Prevalence of: Plasma Alkaline Phosphatase >110 IU/L
Plasma Gamma-Glutamyl Transferase >50/32 IU/L
•Abnormal LFTs in 10% - 30% of all UK adults
•Elevated Alk. Phosphatase - cholestatic liver disease
- reduced excretion of:
Copper and Manganese
and increased mortality
- reduced excretion of:
Copper and Manganese
and increased mortality
•Elevated Gamma GT
- often alcohol excess
- obesity – NAFLD, hepatitis
and drug-induced
- often alcohol excess
- obesity – NAFLD, hepatitis
and drug-induced
•Chronic Liver Disease:
- elevated plasma retinol
- deficiencies of :
vitamins D, B,
- later vitamins A and K
- zinc
- iron accumulation
- elevated plasma retinol
- deficiencies of :
vitamins D, B,
- later vitamins A and K
- zinc
- iron accumulation
