•Abnormal LFTs in 10% - 30% of all UK adults
•
•Elevated Alk. Phosphatase - cholestatic liver disease
- reduced excretion
of:
Copper and
Manganese
and increased mortality
•
•Elevated Gamma GT
- often alcohol
excess
- obesity –
NAFLD, hepatitis
and drug-induced
•
•Chronic Liver Disease:
- elevated plasma
retinol
-
deficiencies of :
vitamins D, B,
- later
vitamins A and K
- zinc
- iron accumulation