Dietary Copper and Fats and Cognitive Decline
Morris MC et al Arch Neurol. 2006;63(8):1085-8
•Dietary intake and cognitive function were assessed in 3,718 community-dwelling participants age 65 years and older living in Chicago over 6 years
•Those with a high dietary intake of saturated or trans fats and a high copper intake had a greater rate of cognitive decline
•Comparing the highest quintile 2.75 mg/day vs lowest quintile 0.88 mg/day the difference in decline was -6.14 units/yr or the equivalent of more than 19 yrs of age
•There was a strong dose-response association with higher dose copper in supplements.
•There was no association in those whose diets were not high in these fats.