•Cause of mortality unknown (mainly vascular
disease and cancer)
•Variety of doses and combinations of
antioxidants used
•Levels of nutrients were not usually assessed
or monitored
•Multivitamin/multimineral preparations were
not used
•Trials do no reflect the use of supplements
in those with proven deficiency
or in situations of increased need
•
•But there are very few trials showing any
benefit of antioxidants